E-AB-81503
Recombinant Dnmt3a Monoclonal Antibody
Größe
£178.20
War £198.00
- SKU:
- E-AB-81503
- Zusätzliche Namen:
- DNA (cytosine 5) methyltransferase 3 alpha,DNA (cytosine 5) methyltransferase 3A,DNA (cytosine-5)-methyltransferase 3A,DNA MTase HsaIII,DNA cytosine methyltransferase 3A2,DNA methyltransferase 3 alpha,DNA methyltransferase 3a,DNA methyltransferase HsaIIIA
- Anwendung:
- WB
- Konzentration:
- 300 ug/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% stabilizer and 0.05% protective protein.
- Immunogen:
- A synthetic peptide of human Dnmt3a
- Klon:
- R03-8H4
- Uniprot:
- Q9Y6K1
- Synonyme:
- cysteine methyltransferase DNMT3A;DNA (cytosine-5-)-methyltransferase 3 alpha;DNA (cytosine-5)-methyltransferase 3A;DNA cytosine methyltransferase 3A2;DNA methyltransferase HsaIIIA;DNA MTase HsaIIIA;DNMT3A2;HESJAS;M.HsaIIIA;TBRS
- Weitere Details:
- CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated. Alternative splicing results in multiple transcript variants encoding different isoforms.
- Versandbedingungen:
- Blue Ice