E-AB-81469
Recombinant FKBP52 Monoclonal Antibody
Größe
£178.20
War £198.00
- SKU:
- E-AB-81469
- Zusätzliche Namen:
- 51 kDa FK506-binding protein,52 kDa FK506 binding protein,52 kDa FK506-binding protein,52 kDa FKBP,59 kDa immunophilin,FK506 binding protein 4,FK506-binding protein 4,FKBP 4,FKBP 52,FKBP 59,FKBP-4,FKBP-52,FKBP4,FKBP51,FKBP52 protein,FKBP59,HBI,Hsp 5
- Anwendung:
- WB, IF
- Konzentration:
- 300 ug/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Hamster, Human, Mouse, Rat
- Buffer:
- 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% stabilizer and 0.05% protective protein.
- Immunogen:
- A synthetic peptide of human FKBP52
- Klon:
- R03-4A3
- Uniprot:
- Q02790
- Synonyme:
- 51 kDa FK506-binding protein;52 kDa FK506-binding protein;59 kDa immunophilin;FK506 binding protein 4, 59kDa;FK506-binding protein 4;FKBP51;FKBP52;FKBP59;HBI;HSP binding immunophilin;HSP-binding immunophilin;Hsp56;Immunophilin FKBP52;p52;peptidyl-prolyl cis-trans isomerase FKBP4;peptidylprolyl cis-trans isomerase;PPIase;rotamase;T-cell FK506-binding protein, 59kD
- Weitere Details:
- FKBP52 (FK506 binding protein 4) is a member of the immunophilin protein family that comprises intracellular protein effectors of immunosuppressive drugs,and it is known as a steroid receptor-associated protein. As a novel regulator of microtubule dynamics,FKBP52 is associated with the motor protein dynein and with the cytoskeleton during mitosis. FKBP52 is highly expressed in CNS regions susceptible to Alzheimer's,and plays a role in modulating toxicity of Abeta peptides. The protein can associate with the Tau function,and may help to decipher and modulate the events involved in Tau-induced neurodegeneration. In addition,FKBP52 is likely to play a role in growth and development of the male genitalia.
- Versandbedingungen:
- Blue Ice