Recombinant ERK2 Monoclonal Antibody

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£178.20

War £198.00

SKU:: E-AB-81446
Zusätzliche Namen:: ERK,ERK 2,ERK-2,ERT1,Extracellular Signal Regulated Kinase 2,Extracellular signal-regulated kinase 2,MAP kinase 1,MAP kinase 2,MAP kinase isoform p42,MAPK 1,MAPK 2,MAPK2,MK01,Mapk1,Mitogen-activated protein kinase 1,Mitogen-activated protein kinase 2,P38
Anwendung:: IHC, WB, IHC-P, IF
Konzentration:: 300 ug/ml
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Elabscience
Host:: Rabbit
Reaktivitäten:: Human, Mouse, Rat
Buffer:: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% stabilizer and 0.05% protective protein.
Immunogen:: A synthetic peptide of human ERK2
Klon:: R07-1A9
Uniprot:: P28482
Synonyme:: ERK;ERK-2;ERK2;ERT1;extracellular signal-regulated kinase 2;MAP kinase 1;MAP kinase 2;MAP kinase isoform p42;MAPK 2;MAPK2;mitogen-activated protein kinase 1;mitogen-activated protein kinase 2;NS13;p38;p40;p41;p41mapk;p42-MAPK;P42MAPK;PRKM1;PRKM2;protein tyrosine kinase ERK2
Weitere Details:: This gene encodes a member of the MAP kinase family.MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development.The activation of this kinase requires its phosphorylation by upstream kinases.Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets.One study also suggests that this protein acts as a transcriptional repressor independent of its kinase activity.The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions.Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene.

Versandbedingungen:: Blue Ice