E-AB-81433
Recombinant Bax Monoclonal Antibody
Größe
£178.20
War £198.00
- SKU:
- E-AB-81433
- Zusätzliche Namen:
- Apoptosis regulator BAX,BAX,BAXA,BCL2 associated X protein,BCL2 associated X protein omega,BCL2 associated X protein transcript variant delta2,BCL2L4,Bax-protein,Baxdelta2G9,Baxdelta2G9omega,Baxdelta2omega,Bcl-2-like protein 4,Bcl2-L-4,membrane isofor
- Anwendung:
- IHC, WB, IHC-P
- Konzentration:
- 300 ug/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% stabilizer and 0.05% protective protein.
- Immunogen:
- A synthetic peptide of human Bax
- Klon:
- R03-1D3
- Uniprot:
- Q07812
- Synonyme:
- apoptosis regulator BAX;Baxdelta2G9;Baxdelta2G9omega;Baxdelta2omega;bcl-2-like protein 4;BCL2 associated X protein;BCL2-associated X protein omega;bcl2-L-4;BCL2L4
- Weitere Details:
- BAX,also named as BCL2L4,is a pro-apoptotic member of the Bcl-2 protein family,which plays a pivotal role in controlling cell life and death. Bax largely localizes to the cytoplasm of healthy cells,but accumulates on the outer mitochondrial membrane upon apoptosis induction . BAX can commit a cell to apoptosis by translocation from the cytosol to the mitochondria and permeabilization of the outer mitochondrial membrane,which leads to the release of cytochrome c from mitochondria . The expression of BAX is upregulated by the tumor suppressor protein p53,and BAX has been shown to be involved in p53-mediated apoptosis .
- Versandbedingungen:
- Blue Ice