E-AB-70333
EGFR Polyclonal Antibody
Größe
£178.20
War £198.00
- SKU:
- E-AB-70333
- Zusätzliche Namen:
- Avian erythroblastic leukemia viral (v erb b) oncogene homolog,Cell growth inhibiting protein 40,Cell proliferation inducing protein 61,EGF R,EGFR,Epide,Epidermal growth factor receptor (avian erythroblastic leukemia viral (v erb b) oncogene homolog)
- Anwendung:
- WB
- Konzentration:
- 1.35 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 1% protein protectant and 50% glycerol.
- Immunogen:
- KLH conjugated Synthetic peptide corresponding to Mouse EGFR
- Uniprot:
- P00533, Q01279
- Synonyme:
- 9030024J15Rik;AI552599;avian erythroblastic leukemia viral (v-erb-b) oncogene homolog;cell growth inhibiting protein 40;cell proliferation-inducing protein 61;epidermal growth factor receptor;epidermal growth factor receptor tyrosine kinase domain;Erb;erb-b2 receptor tyrosine kinase 1;ERBB;ERBB1;Err;Errb1;ERRP;HER1;mENA;NISBD2;PIG61;proto-oncogene c-ErbB-1;receptor tyrosine-protein kinase erbB-1;Wa;wa-2;wa2;Wa5;waved 2
- Weitere Details:
- EGFR,also named as ERBB1,is a cell-surface receptor for members of the epidermal growth factor family (EGF-family) of extracellular protein ligands. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. The gene resides on chromosome 7p12,encoding a 170 kDa membrane-associated glycoprotein. Recent studies have shown EGFR plays a critical role in cancer development and progression,including cell proliferation,apoptosis,angiogenesis,and metastatic spread. Mutations in this gene are associated with lung cancer.
- Versandbedingungen:
- Blue Ice