E-AB-70285
PCNA Polyclonal Antibody
Größe
£178.20
War £198.00
- SKU:
- E-AB-70285
- Zusätzliche Namen:
- ATLD2,Cyclin,DNA polymerase delta auxiliary protein,HGCN8729,MGC8367,Mutagen-sensitive 209 protein,OTTHUMP00000030189,OTTHUMP00000030190,PCNA,PCNAR,Pcna/cyclin,Polymerase delta accessory protein,Proliferating cell nu,cb16,etID36690.10,fa28e03,fb36g03
- Anwendung:
- IHC, WB
- Konzentration:
- 470 ug/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 1% protein protectant and 50% glycerol.
- Immunogen:
- Recombinant protein corresponding to Mouse PCNA
- Uniprot:
- P04961, P17918, Q12004
- Synonyme:
- cyclin;Pcna/cyclin;PCNAR;proliferating cell nuclear antigen;RNA polymerase II transcription factor B 34 kDa subunit;RNA polymerase II transcription factor B p34 subunit;RNA polymerase II transcription factor B subunit 4;TFIIH/NER complex subunit TFB4;YPR056W
- Weitere Details:
- Proliferating Cell Nuclear Antigen,commonly known as PCNA,is a protein that acts as a processivity factor for DNA polymerase D Delta in eukaryotic cells. This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. PCNA induces a robust stimulatory effect on the 3'-5' exonuclease and 3'-phosphodiesterase,but not apurinic-apyrimidinic (AP) endonuclease,APEX2 activities. It has to be loaded onto DNA in order to be able to stimulate APEX2. PCNA protein is highly conserved during evolution, the deduced amino acid sequences of rat and human differ by only 4 of 261 amino acids. PCNA has been used as loading control for proliferating cells.
- Versandbedingungen:
- Blue Ice