S100A4 Polyclonal Antibody

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£178.20

War £198.00

SKU:: E-AB-70283
Zusätzliche Namen:: 18A2,42A,CAPL,Calvasculin,FSP1,Fibroblast specific protein,Fibroblast specific protein 1,Fibroblast specific protein 1 (FSP1),Leukemia multidrug resistance associated protein,Malignan,Malignant transformation suppression 1 (MTS1),calcium Placental protein
Anwendung:: IHC, WB
Konzentration:: 0.75 mg/ml
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Elabscience
Host:: Rabbit
Reaktivitäten:: Human, Mouse, Rat
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 1% protein protectant and 50% glycerol.
Immunogen:: Recombinant protein corresponding to Mouse S100A4
Uniprot:: P05942, P07091, P26447
Synonyme:: 18A;18A2;42A;C;cal;calcium placental protein;calvasculin;CAPL;Fibroblast-specific protein 1;fibroblast-specific protein-1;FS;FSP1;leukemia multidrug resistance associated protein;malignant transformation suppression 1;meta;metastasin;metastasin 1;metastatic cell protein;Mts;MTS1;murine placental homolog;nerve growth factor-induced protein 42A;P9K;P9KA;PeL;PEL98;pk;pk9a;placental calcium-binding protein;protein 18A2;Protein 9 Ka homologous to calcium-binding protein;protein Mts1;protein S100-A4;RNP9KA;S100 calcium-binding protein A4;S100 calcium-binding protein A4 (calcium protein, calvasculin, metastasin, murine placental homolog)
Weitere Details:: S100A4 is a member of the S100 family of calcium-binding proteins. The S100 family members have been involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100A4 is known to localize to and function in the nucleus, cytoplasm of cells and the extracellular space. S100A4 has also been shown to be associated with tumor growth, motility, invasion, metastasis, angiogenesis, apoptosis and chemoresistance. It is a fibroblast-specific protein associated with mesenchymal cell morphology and motility, is expressed during epithelial-mesenchymal transformations (EMT) in vivo. It is an improved marker for lung fibroblasts that could be useful for investigating the pathogenesis of pulmonary fibrosis. Overexpression of S100A4 is correlated with a worse prognosis inpatients with various types of cancer.

Versandbedingungen:: Blue Ice