E-AB-70174
FAS Monoclonal Antibody
Größe
£178.20
War £198.00
- SKU:
- E-AB-70174
- Zusätzliche Namen:
- ALPS 1A,ALPS1A,APO 1,APO 1 cell surface antigen,APO1,APO1 cell surface antigen,APT 1,APT1,Apo 1 antigen,Apo-1 antigen,Apo1 antigen,Apoptosis antigen 1,Apoptosis mediating surface antigen FAS,Apoptosis-mediating surface antigen FAS,CD 95,CD 95 antigen,CD95
- Anwendung:
- IHC
- Konzentration:
- 420 ug/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Mouse
- Reaktivitäten:
- Human, Mouse
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 1% protein protectant and 50% glycerol.
- Immunogen:
- KLH conjugated Synthetic peptide corresponding to Mouse FAS
- Klon:
- 10E5B10
- Uniprot:
- P25445, P25446
- Synonyme:
- AI196731;ALPS1A;AP;APO-1;apo-1 antigen;APO-1 cell surface antigen;APO1;apoptosis antigen 1;apoptosis signaling receptor FAS;apoptosis-mediating surface antigen FAS;APT1;CD95;CD95 antigen;Fas (TNF receptor superfamily member);Fas (TNF receptor superfamily, member 6);Fas AMA;Fas antigen;FAS1;FASLG receptor;FASTM;lpr;lymphoproliferation;mutant tumor necrosis receptor superfamily member 6;TNF;TNF receptor superfamily member 6;Tnfr;TNFR6;TNFRSF6;tumor necrosis factor receptor superfamily member 6;tumor necrosis factor receptor superfamily, member 6
- Weitere Details:
- FAS,also named as CD95,APO-1,APT1,FAS1 and TNFRSF6,is a receptor for TNFSF6/FASLG. It is a cell surface receptor belonging to the TNF receptor superfamily,can mediates apoptosis by ligation with an agonistic anti-Fas antibody or Fas ligand. Stimulation of Fas results in the aggregation of its intracellular death domains,leading to the formation of the death-inducing signaling complex (DISC). FAS-mediated apoptosis may have a role in the induction of peripheral tolerance,in the antigen-stimulated suicide of mature T-cells,or both. The secreted isoforms 2 to 6 block apoptosis (in vitro). This anti-Fas monoclonal antibody can be used to induce apoptosis in cell cultures through Fas by imitating the Fas-ligand.
- Versandbedingungen:
- Blue Ice