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E-AB-70157

Glucocorticoid Receptor Polyclonal Antibody

Größe

£178.20

War £198.00

SKU:
E-AB-70157
Zusätzliche Namen:
GCCR,GCR,GCRST,GR,GRL,Glucocorticoid receptor,Grl1,Nuclear receptor subfamily 3 group C member 1,glucocorticoid nuclear receptor variant 1,group C,member 1 (glucocorticoid receptor),nr3c1,nuclear receptor subfamily 3
Anwendung:
IHC, WB
Konzentration:
1.3 mg/ml
Aufreinigung:
Affinity Purified
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Host:
Rabbit
Reaktivitäten:
Human, Mouse, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 1% protein protectant and 50% glycerol.
Immunogen:
Recombinant proteincorresponding to Mouse Glucocorticoid receptor
Uniprot:
P04150, P06536, P06537
Synonyme:
GCCR;GCR;GCRST;glucocorticoid nuclear receptor variant 1;glucocorticoid receptor;GR;GRL;Nuclear receptor subfamily 3 group C member 1;nuclear receptor subfamily 3 group C member 1 variant hGR-B(54);nuclear receptor subfamily 3 group C member 1 variant hGR-B(77);nuclear receptor subfamily 3 group C member 1 variant hGR-B(93);nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
Weitere Details:
This gene encodes glucocorticoid receptor, which can function both as a transcription factor that binds to glucocorticoid response elements in the promoters of glucocorticoid responsive genes to activate their transcription, and as a regulator of other transcription factors. This receptor is typically found in the cytoplasm, but upon ligand binding, is transported into the nucleus. It is involved in inflammatory responses, cellular proliferation, and differentiation in target tissues. Mutations in this gene are associated with generalized glucocorticoid resistance. Alternative splicing of this gene results in transcript variants encoding either the same or different isoforms.
Versandbedingungen:
Blue Ice