E-AB-70128
MYD88 Polyclonal Antibody
Größe
£178.20
War £198.00
- SKU:
- E-AB-70128
- Zusätzliche Namen:
- MYD 88,MYD88,MYD88D,Mutant myeloid differentiation primary response 88,Myd88,Myeloid differentiation marker 88,Myeloid differentiation primary response 88,Myeloid differentiation primary response gene (88),Myeloid differentiation primary response gene 88
- Anwendung:
- IHC
- Konzentration:
- 110 ug/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 1% protein protectant and 50% glycerol.
- Immunogen:
- KLH conjugated Synthetic peptide corresponding to Mouse MYD88
- Uniprot:
- P22366, Q6Y1S1
- Synonyme:
- myeloid differentiation primary response 88;myeloid differentiation primary response gene 88;myeloid differentiation primary response protein 88;myeloid differentiation primary response protein MyD88
- Weitere Details:
- This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants.
- Versandbedingungen:
- Blue Ice