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E-AB-70112

AR Polyclonal Antibody

Größe

£178.20

War £198.00

SKU:
E-AB-70112
Zusätzliche Namen:
AIS,ANDR,AR,AR8,Androgen nuclear receptor variant 2,Androgen receptor,Androgen receptor (dihydrotestosterone receptor,DHTR,Dihydro testosterone,Kennedy disease),androgen receptor splice variant 4b,spinal and bulbar muscular atrophy,testicular feminization
Anwendung:
IHC
Konzentration:
0.83 mg/ml
Aufreinigung:
Affinity Purified
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Host:
Rabbit
Reaktivitäten:
Human, Mouse, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 1% protein protectant and 50% glycerol.
Immunogen:
KLH conjugated Synthetic peptide corresponding to Mouse Androgen receptor
Uniprot:
P10275, P15207, P19091
Synonyme:
AIS;Andr;androgen receptor;androgen receptor (Testicular feminization), same as Tfm;AR8;AW320017;DHTR;dihydrotestosterone receptor;HUMARA;HYSP1;KD;NR3C4;nuclear receptor subfamily 3 group C member 4;SBMA;SMAX1;testicular feminization;TFM
Weitere Details:
The androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N-terminal domain, DNA-binding domain, and androgen-binding domain.The protein functions as a steroid-hormone activated transcription factor.Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes.This gene contains 2 polymorphic trinucleotide repeat segments that encode polyglutamine and polyglycine tracts in the N-terminal transactivation domain of its protein.
Versandbedingungen:
Blue Ice