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E-AB-70107

MMP13 Polyclonal Antibody

Größe

£178.20

War £198.00

SKU:
E-AB-70107
Zusätzliche Namen:
CLG 3,CLG3,Collagenase 3,Collagenase3,MANDP1,MMP 13,MMP-13,MMP13,Matrix Metalloproteinase 13,Matrix metallopeptidase 13 (collagenase 3),Matrix metalloproteinase-13,Mmp13
Anwendung:
IHC
Konzentration:
200 ug/ml
Aufreinigung:
Affinity Purified
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Host:
Rabbit
Reaktivitäten:
Mouse, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 1% protein protectant and 50% glycerol.
Immunogen:
KLH conjugated Synthetic peptide corresponding to Mouse MMP13
Uniprot:
P23097, P33435
Synonyme:
Cl;Clg;collagenase 3;collagenase-1;interstitial collagenase;matrix metalloproteinase 13;Matrix metalloproteinase-13;Mmp;MMP-1;MMP-13;Mmp1;UMRCASE
Weitere Details:
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene cleaves type II collagen more efficiently than types I and III. It may be involved in articular cartilage turnover and cartilage pathophysiology associated with osteoarthritis. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.
Versandbedingungen:
Blue Ice