E-AB-70087
CHOP Polyclonal Antibody
Größe
£178.20
War £198.00
- SKU:
- E-AB-70087
- Zusätzliche Namen:
- C/EBP Homology Protein,C/EBP homologous protein,C/EBP zeta,C/EBP-homologous protein,C/EBP-homologous protein 10,CCAAT/enhancer binding protein homologous protein,CEBPZ,CHOP,CHOP 10,CHOP-10,CHOP10,DDIT 3,DDIT-3,DDIT3,DNA Damage Inducible Transcript 3,Ddit3
- Anwendung:
- IHC
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 1% protein protectant and 50% glycerol.
- Immunogen:
- KLH conjugated Synthetic peptide corresponding to Mouse CHOP
- Uniprot:
- P35638, P35639, Q62857
- Synonyme:
- AltDDIT3;alternative DDIT3 protein;alternative DDIT3 proteins;C/EBP homoologous protein 10;C/EBP zeta;C/EBP-homologous protein;c/EBP-homologous protein 10;C/EBPzeta;CCAAT/enhancer-binding protein homologous protein;CEBPZ;ch;CHOP;CHOP-;CHOP-10;CHOP10;DDIT-3;DNA damage-inducible transcript 3 protein;gadd15;GADD153;growth arrest and DNA damage-inducible protein GADD153;growth arrest and DNA-damage-inducible protein GADD153
- Weitere Details:
- CHOP,also known as GADD153 or DDIT3,is a highly conserved gene in both the structural and regulatory regions to hamster gene.Imposed by unfolded and malfolded proteins,CHOP is significantly induced by ER stress,deficiency of CHOP prevents cell from ER stress. CHOP is considered a proapoptotic marker of ER stress dependent cell death. CHOP acts as a dominant-negative inhibitor of the transcription factor C/EBP and LAP by forming a heterodimer. It may play an important role in the malignant transformation of nevus to melanoma.
- Versandbedingungen:
- Blue Ice