E-AB-70080
FLK1 Polyclonal Antibody
Größe
£178.20
War £198.00
- SKU:
- E-AB-70080
- Zusätzliche Namen:
- CD309,CD309 antigen,EC 2.7.10.1,FLK-1,FLK1,Fetal liver kinase 1,KRD1,Kdr,Kinase insert domain receptor,Kinase insert domain receptor (a type III receptor tyrosine kinase),Ly73,Protein tyrosine kinase receptor FLK1,Protein-tyrosine ki,homolog of,mouse
- Anwendung:
- WB
- Konzentration:
- 1.1 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 1% protein protectant and 50% glycerol.
- Immunogen:
- KLH conjugated Synthetic peptide corresponding to Mouse VEGFR2
- Uniprot:
- O08775, P35918, P35968
- Synonyme:
- CD309;fetal liver kinase 1;fetal liver kinase-1;FLK-1;FLK1;FLK1 kinase insert domain receptor (a type III receptor tyrosine kinase) (VEGF receptor 2);FLK1 kinase insert domain receptor (VEGF receptor 2);kinase insert domain protein receptor;Kinase insert domain receptor;kinase insert domain receptor (a type III receptor tyrosine kinase);Kinase NYK;protein-tyrosine kinase receptor Flk-1;soluble VEGFR2;tyrosine kinase growth factor receptor;vascular endothelial growth factor receptor 2;VEGFR;Vegfr-2;VEGFR2
- Weitere Details:
- Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc. Mutations of this gene are implicated in infantile capillary hemangiomas.
- Versandbedingungen:
- Blue Ice