E-AB-70057
MMP2 Polyclonal Antibody
Größe
£178.20
War £198.00
- SKU:
- E-AB-70057
- Zusätzliche Namen:
- 72 kDa gelatinase,72kD type IV collagenase,CLG 4,CLG 4A,CLG4,CLG4A,Collagenase Type 4 alpha,Collagenase type IV A,Gelatinase A,Gelatinase alpha,Gelatinase neutrophil,Matrix ,Matrix metallopeptidase 2 gelatinase A 72kDa gelatinase 72kDa type IV collagenase
- Anwendung:
- IHC
- Konzentration:
- 0.82 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 1% protein protectant and 50% glycerol.
- Immunogen:
- KLH conjugated Synthetic peptide corresponding to Mouse MMP2
- Uniprot:
- P08253, P33434, P33436
- Synonyme:
- 72 kDa gelatinase;72 kDa type IV collagenase;72kD gelatinase;72kD type IV collagenase;72kDa gelatinase;72kDa type IV collagenase;Clg;CLG4;CLG4A;collagenase type IV-A;Ge;GelA;gelatinase A;matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase);matrix metalloproteinase 2;matrix metalloproteinase-2;matrix metalloproteinase-II;MMP-;MMP-2;MMP-II;MONA;neutrophil gelatinase;TBE-1
- Weitere Details:
- MMP2,also named as CLG4A,Gelatinase Am,TBE-1 and PEX,belongs to the peptidase M10A family. It is ubiquitinous metalloproteinase that is involved in diverse functions such as remodeling of the vasculature,angiogenesis,tissue repair,tumor invasion,inflammation,and atherosclerotic plaque rupture. MMP2 contributes to myocardial oxidative stress by regulating the activity of GSK3beta. It cleaves GSK3beta in vitro. MMP2 can be cleaved into PEX chain(~60kd).Western blot analysis showed that the 72 kDa and 62 kDa proteinase activities were pro-MMP2 and the active enzyme,respectively.
- Versandbedingungen:
- Blue Ice