E-AB-68430
DSG1 Polyclonal Antibody
Größe
£195.30
War £217.00
- SKU:
- E-AB-68430
- Zusätzliche Namen:
- CDHF4,DG1,DSG,DSG1,EPKHE,EPKHIA,PPKS1,SPPK1
- Anwendung:
- WB, IF
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human DSG1
- Uniprot:
- Q02413
- Synonyme:
- cadherin family member 4;CDHF4;desmoglein-1;desmosomal glycoprotein 1;DG1;DSG;EPKHE;EPKHIA;pemphigus foliaceus antigen;PPKS1;SPPK1
- Weitere Details:
- This gene encodes a member of the desmoglein protein subfamily. Desmogleins, along with desmocollins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmoglein family members on chromosome 18. The encoded protein has been identified as a target of auto-antibodies in the autoimmune skin blistering disease pemphigus foliaceus. Disruption of this gene has also been associated with the skin diseases palmoplantar keratoderma and erythroderma.
- Versandbedingungen:
- Blue Ice