E-AB-68406
MYH7 Polyclonal Antibody
Größe
£195.30
War £217.00
- SKU:
- E-AB-68406
- Zusätzliche Namen:
- CMD1S,CMH1,MPD1,MYH7,MYH7 ,MYHCB,SPMD,SPMM,myosin-7
- Anwendung:
- WB, IF
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human MYH7
- Uniprot:
- P12883
- Synonyme:
- cardiac muscle myosin heavy chain 7 beta;CMD1S;CMH1;MPD1;myHC-beta;myhc-slow;MYHCB;myopathy, distal 1;myosin 7;Myosin heavy chain 7;myosin heavy chain beta-subunit;Myosin heavy chain slow isoform;Myosin heavy chain, cardiac muscle beta isoform;myosin-7;myosin, heavy chain 7, cardiac muscle, beta;myosin, heavy polypeptide 7, cardiac muscle, beta;rhabdomyosarcoma antigen MU-RMS-40.7A;SPMD;SPMM
- Weitere Details:
- Muscle myosin is a hexameric protein containing 2 heavy chain subunits, 2 alkali light chain subunits, and 2 regulatory light chain subunits. This gene encodes the beta (or slow) heavy chain subunit of cardiac myosin. It is expressed predominantly in normal human ventricle. It is also expressed in skeletal muscle tissues rich in slow-twitch type I muscle fibers. Changes in the relative abundance of this protein and the alpha (or fast) heavy subunit of cardiac myosin correlate with the contractile velocity of cardiac muscle. Its expression is also altered during thyroid hormone depletion and hemodynamic overloading. Mutations in this gene are associated with familial hypertrophic cardiomyopathy, myosin storage myopathy, dilated cardiomyopathy, and Laing early-onset distal myopathy.
- Versandbedingungen:
- Blue Ice