E-AB-68401
ITLN1 Polyclonal Antibody
Größe
£195.30
War £217.00
- SKU:
- E-AB-68401
- Zusätzliche Namen:
- HL-1,HL1,INTL,ITLN,ITLN1,LFR,hIntL,omentin
- Anwendung:
- IHC, WB, IF
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human ITLN1
- Uniprot:
- Q8WWA0
- Synonyme:
- endothelial lectin HL-1;galactofuranose-binding lectin;hIntL;HL-1;HL1;intelectin 1 (galactofuranose binding);intelectin-1;intestinal lactoferrin receptor;INTL;ITLN;ITLN-1;LFR;omentin
- Weitere Details:
- Intelectin-1(ITLN1) is a secreted protein and contains 1 fibrinogen C-terminal domain. Intelectin-1 is a 40 kDaCa-dependent galactofuranose-binding lectin that is not a C-type lectin. It is expressed on multiple cell typesand appears to participate in insulin signaling and microbe recognition. The protein has no effect on basalglucose uptake but enhances insulin-stimulated glucose uptake in adipocytes. It increases AKT phosphorylationin the absence and presence of insulin and it may play a role in the defense systemagainst microorganisms. Italso may specifically recognize carbohydrate chains of pathogens and bacterial components containinggalactofuranosy l residues, in a calcium-dependent manner.
- Versandbedingungen:
- Blue Ice