E-AB-68362
ITGA6 Polyclonal Antibody
Größe
£195.30
War £217.00
- SKU:
- E-AB-68362
- Zusätzliche Namen:
- CD49f,ITGA6,ITGA6B,Integrin alpha 6,VLA-6
- Anwendung:
- WB
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human ITGA6
- Uniprot:
- P23229
- Synonyme:
- CD49 antigen-like family member F;CD49f;integrin alpha-6;integrin alpha6B;integrin, alpha 6;ITGA6B;VLA-6
- Weitere Details:
- The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 6 subunit. This subunit may associate with a beta 1 or beta 4 subunit to form an integrin that interacts with extracellular matrix proteins including members of the laminin family. The alpha 6 beta 4 integrin may promote tumorigenesis, while the alpha 6 beta 1 integrin may negatively regulate erbB2/HER2 signaling. Alternative splicing results in multiple transcript variants.
- Versandbedingungen:
- Blue Ice