E-AB-68357
Occludin Polyclonal Antibody
Größe
£211.50
War £235.00
- SKU:
- E-AB-68357
- Zusätzliche Namen:
- BLCPMG,OCLN,Occludin,PPP1R115,PTORCH1,occludin
- Anwendung:
- WB
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human Occludin
- Uniprot:
- Q16625
- Synonyme:
- BLCPMG;occludin;phosphatase 1, regulatory subunit 115;PPP1R115;PTORCH1
- Weitere Details:
- This gene encodes an integral membrane protein that is required for cytokine-induced regulation of the tight junction paracellular permeability barrier. Mutations in this gene are thought to be a cause of band-like calcification with simplified gyration and polymicrogyria (BLC-PMG), an autosomal recessive neurologic disorder that is also known as pseudo-TORCH syndrome. Alternative splicing results in multiple transcript variants. A related pseudogene is present 1.5 Mb downstream on the q arm of chromosome 5.
- Versandbedingungen:
- Blue Ice