TRPV1 Polyclonal Antibody

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£195.30

War £217.00

SKU:: E-AB-67999
Zusätzliche Namen:: TRPV1,VR1
Anwendung:: IF
Konzentration:: 1 mg/ml
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Elabscience
Host:: Rabbit
Reaktivitäten:: Human, Mouse, Rat
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:: A synthetic peptide of human TRPV1 (NP_061197.4).
Uniprot:: Q8NER1
Synonyme:: capsaicin receptor;osm-9-like TRP channel 1;OTRPC1;transient receptor potential cation channel subfamily V member 1;transient receptor potential vanilloid 1a;transient receptor potential vanilloid 1b;Vanilloid receptor 1;vanilloid receptor subtype 1;VR1
Weitere Details:: Capsaicin, the main pungent ingredient in hot chili peppers, elicits a sensation of burning pain by selectively activating sensory neurons that convey information about noxious stimuli to the central nervous system. The protein encoded by this gene is a receptor for capsaicin and is a non-selective cation channel that is structurally related to members of the TRP family of ion channels. This receptor is also activated by increases in temperature in the noxious range, suggesting that it functions as a transducer of painful thermal stimuli in vivo. Four transcript variants encoding the same protein, but with different 5' UTR sequence, have been described for this gene.