SLC12A6 Polyclonal Antibody

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£195.30

War £217.00

SKU:: E-AB-67960
Zusätzliche Namen:: ACCPN,KCC3,KCC3A,KCC3B,SLC12A6
Anwendung:: IF
Konzentration:: 1 mg/ml
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Elabscience
Host:: Rabbit
Reaktivitäten:: Human
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:: Recombinant fusion protein of human SLC12A6 (NP_598408.1).
Uniprot:: Q9UHW9
Synonyme:: ACCPN;electroneutral potassium-chloride cotransporter 3;K-Cl cotransporter 3;KCC3;KCC3A;KCC3B;potassium chloride cotransporter 3;potassium chloride cotransporter KCC3a-S3;potassium-chloride transporter-3a;potassium-chloride transporter-3b;solute carrier family 12 (potassium/chloride transporter), member 6;solute carrier family 12 (potassium/chloride transporters), member 6;solute carrier family 12 member 6
Weitere Details:: This gene is a member of the K-Cl cotransporter (KCC) family. K-Cl cotransporters are integral membrane proteins that lower intracellular chloride concentrations below the electrochemical equilibrium potential. The proteins encoded by this gene are activated by cell swelling induced by hypotonic conditions. Alternate splicing results in multiple transcript variants encoding different isoforms. Mutations in this gene are associated with agenesis of the corpus callosum with peripheral neuropathy.