TROVE2 Polyclonal Antibody

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£195.30

War £217.00

SKU:: E-AB-67807
Zusätzliche Namen:: RO60,RORNP,SSA2,TROVE2
Anwendung:: WB
Konzentration:: 1 mg/ml
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Elabscience
Host:: Rabbit
Reaktivitäten:: Human, Mouse, Rat
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:: Recombinant fusion protein of human TROVE2
Uniprot:: P10155
Synonyme:: 60 kDa ribonucleoprotein Ro;60 kDa SS-A/Ro ribonucleoprotein;gastric cancer multi-drug resistance protein;Ro 60 kDa autoantigen;Ro/SSA 60kDa;ro60 autoantigen;RORNP;Sjoegren syndrome antigen A2;sjoegren syndrome type A antigen;Sjogren syndrome antigen A2 (60kD, ribonucleoprotein autoantigen SS-A/Ro);SSA2;TROVE domain family member 2;TROVE2
Weitere Details:: RNA-binding protein that binds to misfolded non-coding RNAs, pre-5S rRNA, and several small cytoplasmic RNA molecules known as Y RNAs. May stabilize some of these RNAs and protect them from degradation. Binds to endogenous Alu retroelements which are induced by type I interferon and stimulate porinflammaotry cytokine secretion. Regulates the expression of Alu retroelements as well as inflammatory genes.