WWP1 Polyclonal Antibody

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£195.30

War £217.00

SKU:: E-AB-67637
Zusätzliche Namen:: AIP5,Tiul1,WWP1,hSDRP1
Anwendung:: WB
Konzentration:: 1 mg/ml
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Elabscience
Host:: Rabbit
Reaktivitäten:: Human, Mouse
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:: Recombinant fusion protein of human WWP1 (NP_008944.1).
Uniprot:: Q9H0M0
Synonyme:: AIP5;atrophin-1 interacting protein 5;Atrophin-1-interacting protein 5;HECT-type E3 ubiquitin transferase WWP1;hSDRP1;Nedd-4-like ubiquitin-protein ligase;NEDD4-like E3 ubiquitin-protein ligase WWP1;TGIF-interacting ubiquitin ligase 1;Tiul1;WW domain-containing protein 1
Weitere Details:: WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein which contains 4 tandem WW domains and a HECT (homologous to the E6-associated protein carboxyl terminus) domain. The encoded protein belongs to a family of NEDD4-like proteins, which are E3 ubiquitin-ligase molecules and regulate key trafficking decisions, including targeting of proteins to proteosomes or lysosomes. Alternative splicing of this gene generates at least 6 transcript variants, however, the full length nature of these transcripts has not been defined.