SRSF2 Polyclonal Antibody

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£195.30

War £217.00

SKU:: E-AB-67585
Zusätzliche Namen:: PR264,SC-35,SC35,SFRS2,SFRS2A,SRSF2,SRp30b
Anwendung:: WB
Konzentration:: 1 mg/ml
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Elabscience
Host:: Rabbit
Reaktivitäten:: Human, Mouse, Rat
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:: Recombinant fusion protein of human SRSF2 (NP_003007.2).
Uniprot:: Q01130
Synonyme:: PR264;Protein PR264;SC-35;SC35;serine/arginine-rich splicing factor 2;SFRS2;SFRS2A;splicing component, 35 kDa;splicing factor SC35;splicing factor, arginine/serine-rich 2;SR splicing factor 2;SRp30b
Weitere Details:: The protein encoded by this gene is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM) for binding RNA and an RS domain for binding other proteins. The RS domain is rich in serine and arginine residues and facilitates interaction between different SR splicing factors. In addition to being critical for mRNA splicing, the SR proteins have also been shown to be involved in mRNA export from the nucleus and in translation. Two transcript variants encoding the same protein and one non-coding transcript variant have been found for this gene. In addition, a pseudogene of this gene has been found on chromosome 11.