E-AB-67543
HNF1A Polyclonal Antibody
Größe
£195.30
War £217.00
- SKU:
- E-AB-67543
- Zusätzliche Namen:
- HNF-1A,HNF1,HNF1A,IDDM20,LFB1,MODY3,TCF-1,TCF1
- Anwendung:
- WB
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- A synthetic peptide of human HNF1A
- Uniprot:
- P20823
- Synonyme:
- albumin proximal factor;hepatic nuclear factor 1;hepatocyte nuclear factor 1-alpha;HNF-1-alpha;HNF-1A;HNF1;HNF1alpha;HNF4A;IDDM20;interferon production regulator factor;LFB1;liver-specific transcription factor LF-B1;MODY3;TCF-1;TCF1;Transcription factor 1;transcription factor 1, hepatic;truncated hepatocyte nuclear factor 1 alpha
- Weitere Details:
- The protein encoded by this gene is a transcription factor required for the expression of several liver-specific genes. The encoded protein functions as a homodimer and binds to the inverted palindrome 5'-GTTAATNATTAAC-3'. Defects in this gene are a cause of maturity onset diabetes of the young type 3 (MODY3) and also can result in the appearance of hepatic adenomas. Alternative splicing results in multiple transcript variants encoding different isoforms.
- Versandbedingungen:
- Blue Ice