APCS Polyclonal Antibody

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£195.30

War £217.00

SKU:: E-AB-67395
Zusätzliche Namen:: APCS,HEL-S-92n,PTX2,SAP
Anwendung:: IHC
Konzentration:: 1 mg/ml
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Elabscience
Host:: Rabbit
Reaktivitäten:: Human, Mouse, Rat
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:: Recombinant fusion protein of human APCS (NP_001630.1).
Uniprot:: P02743
Synonyme:: 9.5S alpha-1-glycoprotein;epididymis secretory sperm binding protein Li 92n;HEL-S-92n;pentaxin-related;pentraxin-2;pentraxin-related;PTX2;SAP;serum amyloid P-component
Weitere Details:: The protein encoded by this gene is a glycoprotein, belonging to the pentraxin family of proteins, which has a characteristic pentameric organization. These family members have considerable sequence homology which is thought to be the result of gene duplication. The binding of the encoded protein to proteins in the pathological amyloid cross-beta fold suggests its possible role as a chaperone. This protein is also thought to control the degradation of chromatin. It has been demonstrated that this protein binds to apoptotic cells at an early stage, which raises the possibility that it is involved in dealing with apoptotic cells in vivo.