E-AB-67309
CYSLTR1 Polyclonal Antibody
Größe
£195.30
War £217.00
- SKU:
- E-AB-67309
- Zusätzliche Namen:
- CYSLT1,CYSLT1R,CYSLTR,CYSLTR1,HMTMF81
- Anwendung:
- WB
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- A synthetic peptide of human CYSLTR1 (NP_006630.1).
- Uniprot:
- Q9Y271
- Synonyme:
- CYSLT1;CYSLT1R;CYSLTR;cysteinyl leukotriene D4 receptor;cysteinyl leukotriene receptor 1;G-protein coupled receptor HG55;HMTMF81;LTD4 receptor
- Weitere Details:
- This gene encodes a member of the G-protein coupled receptor 1 family. The encoded protein is a receptor for cysteinyl leukotrienes, and is involved in mediating bronchoconstriction via activation of a phosphatidylinositol-calcium second messenger system. Activation of the encoded receptor results in contraction and proliferation of bronchial smooth muscle cells, eosinophil migration, and damage to the mucus layer in the lung. Upregulation of this gene is associated with asthma and dysregulation may also be implicated in cancer. Alternative splicing results in multiple transcript variants.
- Versandbedingungen:
- Blue Ice