E-AB-67211
BUB1B Polyclonal Antibody
Größe
£195.30
War £217.00
- SKU:
- E-AB-67211
- Zusätzliche Namen:
- BUB1B,BUB1beta,BUBR1,Bub1A,MAD3L,MVA1,SSK1,hBUBR1
- Anwendung:
- WB, IF
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human BUB1B
- Uniprot:
- O60566
- Synonyme:
- Bub1A;BUB1B, mitotic checkpoint serine/threonine kinase;BUB1beta;BUBR1;budding uninhibited by benzimidazoles 1 homolog beta;hBUBR1;MAD3/BUB1-related protein kinase;MAD3L;mitotic checkpoint kinase MAD3L;mitotic checkpoint serine/threonine-protein kinase BUB1 beta;MVA1;Protein SSK1;SSK1
- Weitere Details:
- This gene encodes a kinase involved in spindle checkpoint function. The protein has been localized to the kinetochore and plays a role in the inhibition of the anaphase-promoting complex/cyclosome (APC/C), delaying the onset of anaphase and ensuring proper chromosome segregation. Impaired spindle checkpoint function has been found in many forms of cancer.
- Versandbedingungen:
- Blue Ice