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E-AB-67028

TAX1BP1 Polyclonal Antibody

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£195.30

War £217.00

SKU:
E-AB-67028
Zusätzliche Namen:
CALCOCO3,T6BP,TAX1BP1,TXBP151
Anwendung:
IHC
Konzentration:
1 mg/ml
Aufreinigung:
Affinity Purified
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Host:
Rabbit
Reaktivitäten:
Human, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Recombinant fusion protein of human TAX1BP1 (NP_006015.4).
Uniprot:
Q86VP1
Synonyme:
CALCOCO3;T6BP;Tax1 (human T-cell leukemia virus type I) binding protein 1;tax1-binding protein 1;TRAF6-binding protein;TXBP151
Weitere Details:
This gene encodes a HTLV-1 tax1 binding protein. The encoded protein interacts with TNFAIP3, and inhibits TNF-induced apoptosis by mediating the TNFAIP3 anti-apoptotic activity. Degradation of this protein by caspase-3-like family proteins is associated with apoptosis induced by TNF. This protein may also have a role in the inhibition of inflammatory signaling pathways. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Versandbedingungen:
Blue Ice