ADARB1 Polyclonal Antibody

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£195.30

War £217.00

SKU:: E-AB-66927
Zusätzliche Namen:: ADAR2,ADARB1,DRABA2,DRADA2,RED1
Anwendung:: WB
Konzentration:: 1 mg/ml
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Elabscience
Host:: Rabbit
Reaktivitäten:: Human, Mouse, Rat
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:: Recombinant fusion protein of human ADARB1 (NP_001103.1).
Uniprot:: P78563
Synonyme:: ADAR2;adenosine deaminase, RNA-specific, B1 (homolog of rat RED1);double-stranded RNA-specific editase 1;DRABA2;DRADA2;dsRNA adenosine deaminase;dsRNA adenosine deaminase DRADA2;NEDHYMS;RED1;RNA editing deaminase 1;RNA-editing deaminase 1;RNA-editing enzyme 1
Weitere Details:: This gene encodes the enzyme responsible for pre-mRNA editing of the glutamate receptor subunit B by site-specific deamination of adenosines. Studies in rat found that this enzyme acted on its own pre-mRNA molecules to convert an AA dinucleotide to an AI dinucleotide which resulted in a new splice site. Alternative splicing of this gene results in several transcript variants, some of which have been characterized by the presence or absence of an ALU cassette insert and a short or long C-terminal region.