NRP1 Polyclonal Antibody

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£211.50

War £235.00

SKU:: E-AB-66905
Zusätzliche Namen:: BDCA4,CD304,NP1,NRP,NRP1,Neuropilin-1,VEGF165R
Anwendung:: WB, IF
Konzentration:: 1 mg/ml
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Elabscience
Host:: Rabbit
Reaktivitäten:: Human, Mouse, Rat
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:: Recombinant fusion protein of human NRP1 (NP_001019800.1).
Uniprot:: O14786
Synonyme:: BDCA4;CD304;neuropilin-1;NP1;NRP;transmembrane receptor;vascular endothelial cell growth factor 165 receptor;VEGF165R
Weitere Details:: This gene encodes one of two neuropilins, which contain specific protein domains which allow them to participate in several different types of signaling pathways that control cell migration. Neuropilins contain a large N-terminal extracellular domain, made up of complement-binding, coagulation factor V/VIII, and meprin domains. These proteins also contains a short membrane-spanning domain and a small cytoplasmic domain. Neuropilins bind many ligands and various types of co-receptors, they affect cell survival, migration, and attraction. Some of the ligands and co-receptors bound by neuropilins are vascular endothelial growth factor (VEGF) and semaphorin family members. Several alternatively spliced transcript variants that encode different protein isoforms have been described for this gene.