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E-AB-66839

COMMD5 Polyclonal Antibody

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£195.30

War £217.00

SKU:
E-AB-66839
Zusätzliche Namen:
COMMD5,HCARG,HT002
Anwendung:
IF
Konzentration:
1 mg/ml
Aufreinigung:
Affinity Purified
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Host:
Rabbit
Reaktivitäten:
Human, Mouse, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Recombinant fusion protein of human COMMD5 (NP_054785.2).
Uniprot:
Q9GZQ3
Synonyme:
COMM domain-containing protein 5;HCARG;HT002;hypertension-related calcium-regulated gene protein
Weitere Details:
May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes. Negatively regulates cell proliferation. Negatively regulates cell cycle G2/M phase transition probably by transactivating p21/CDKN1A through the p53/TP53-independent signaling pathway. Involved in kidney proximal tubule morphogenesis. Down-regulates activation of NF-kappa-B.
Versandbedingungen:
Blue Ice