FKBP1B Polyclonal Antibody

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£195.30

War £217.00

SKU:: E-AB-66786
Zusätzliche Namen:: FKBP12.6,FKBP1B,FKBP1L,OTK4,PKBP1L,PPIase
Anwendung:: IHC, IF
Konzentration:: 1 mg/ml
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Elabscience
Host:: Rabbit
Reaktivitäten:: Human, Mouse, Rat
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:: A synthetic peptide of human FKBP1B (NP_473374.1).
Uniprot:: P68106
Synonyme:: 12.6 kDa FK506-binding protein;12.6 kDa FKBP;calstabin 2;FK506 binding protein 1B, 12.6 kDa;FK506-binding protein 12.6;FK506-binding protein 1B;FKBP-12.6;FKBP-1B;FKBP12.6;FKBP1L;h-FKBP-12;immunophilin FKBP12.6;OTK4;peptidyl-prolyl cis-trans isomerase FKBP1B;PKBP1L;PPIase;PPIase FKBP1B;rotamase
Weitere Details:: The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It is highly similar to the FK506-binding protein 1A. Its physiological role is thought to be in excitation-contraction coupling in cardiac muscle. There are two alternatively spliced transcript variants of this gene encoding different isoforms.