TRIM27 Polyclonal Antibody

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£195.30

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SKU:: E-AB-66677
Zusätzliche Namen:: RFP,RNF76,TRIM27
Anwendung:: IHC
Konzentration:: 1 mg/ml
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Elabscience
Host:: Rabbit
Reaktivitäten:: Human, Mouse, Rat
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:: Recombinant fusion protein of human TRIM27 (NP_006501.1).
Uniprot:: P14373
Synonyme:: ret finger protein;RFP;RFP transforming protein;RING finger protein 76;RING-type E3 ubiquitin transferase TRIM27;RNF76;tripartite motif protein TRIM27;tripartite motif-containing protein 27;zinc finger protein RFP
Weitere Details:: This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to the nuclear matrix. It interacts with the enhancer of polycomb protein and represses gene transcription. It is also thought to be involved in the differentiation of male germ cells. Fusion of the N-terminus of this protein with the truncated C-terminus of the RET gene product has been shown to result in production of the ret transforming protein.