KIF13A Polyclonal Antibody

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£195.30

War £217.00

SKU:: E-AB-66611
Zusätzliche Namen:: KIF13A,RBKIN,bA500C11.2
Anwendung:: IF
Konzentration:: 1 mg/ml
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Elabscience
Host:: Rabbit
Reaktivitäten:: Human, Mouse
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:: Recombinant fusion protein of human KIF13A (NP_001099036.1).
Uniprot:: Q9H1H9
Synonyme:: bA500C11.2;homolog of mouse KIF13A mannose-6-phosphate receptor transporter;kinesin-like protein KIF13A;kinesin-like protein RBKIN;RBKIN
Weitere Details:: This gene encodes a member of the kinesin family of microtubule-based motor proteins that function in the positioning of endosomes. This family member can direct mannose-6-phosphate receptor-containing vesicles from the trans-Golgi network to the plasma membrane, and it is necessary for the steady-state distribution of late endosomes/lysosomes. It is also required for the translocation of FYVE-CENT and TTC19 from the centrosome to the midbody during cytokinesis, and it plays a role in melanosome maturation. Alternative splicing of this gene results in multiple transcript variants.