E-AB-66600
ASCC1 Polyclonal Antibody
Größe
£195.30
War £217.00
- SKU:
- E-AB-66600
- Zusätzliche Namen:
- ASC1p50,ASCC1,CGI-18,SMABF2,p50
- Anwendung:
- WB
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human ASCC1 (NP_001185727.1).
- Uniprot:
- Q8N9N2
- Synonyme:
- activating signal cointegrator 1 complex subunit 1;ASC-1 complex subunit P50;ASC1p50;CGI-18;p50;SMABF2;trip4 complex subunit p50
- Weitere Details:
- This gene encodes a subunit of the activating signal cointegrator 1 (ASC-1) complex. The ASC-1 complex is a transcriptional coactivator that plays an important role in gene transactivation by multiple transcription factors including activating protein 1 (AP-1), nuclear factor kappa-B (NF-kB) and serum response factor (SRF). The encoded protein contains an N-terminal KH-type RNA-binding motif which is required for AP-1 transactivation by the ASC-1 complex. Mutations in this gene are associated with Barrett esophagus and esophageal adenocarcinoma. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene.
- Versandbedingungen:
- Blue Ice