E-AB-66410
GYPB Polyclonal Antibody
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£195.30
War £217.00
- SKU:
- E-AB-66410
- Zusätzliche Namen:
- CD235b,GPB,GYP,GYPB,MNS,PAS-3,SS
- Anwendung:
- IF
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human GYPB (NP_002091.3).
- Uniprot:
- P06028
- Synonyme:
- blood group system MNSs, Mur-like;blood group system MNSs, St(a) type E;blood group system MNSs, St(a) type F;CD235b;glycophorin A;glycophorin B blood group antigen;glycophorin B, blood group system Ss, S, Mit+;glycophorin B/glycophorin A fusion protein;glycophorin Hop;glycophorin-B;GPB;GYP;GYPA;GYPB-A fusion;GYPB-A-B fusion;GYPB/GYPA fusion;hybrid glycophorin Kip;MNS;PAS-3;sialoglycoprotein delta;SS;Ss blood group;SS-active sialoglycoprotein
- Weitere Details:
- Glycophorins A (GYPA) and B (GYPB) are major sialoglycoproteins of the human erythrocyte membrane which bear the antigenic determinants for the MN and Ss blood groups. GYPB gene consists of 5 exons and has 97% sequence homology with GYPA from the 5' UTR to the coding sequence encoding the first 45 amino acids. In addition to the M or N and S or s antigens, that commonly occur in all populations, about 40 related variant phenotypes have been identified. These variants include all the variants of the Miltenberger complex and several isoforms of Sta, also, Dantu, Sat, He, Mg, and deletion variants Ena, S-s-U- and Mk. Most of the variants are the result of gene recombinations between GYPA and GYPB. Alternate splicing results in multiple transcript variants.
- Versandbedingungen:
- Blue Ice