CYP11B1 Polyclonal Antibody

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£195.30

War £217.00

SKU:: E-AB-66405
Zusätzliche Namen:: CPN1,CYP11B,CYP11B1,FHI,P450C11
Anwendung:: IF
Konzentration:: 1 mg/ml
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Elabscience
Host:: Rabbit
Reaktivitäten:: Human
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:: Recombinant fusion protein of human CYP11B1 (NP_000488.3).
Uniprot:: P15538
Synonyme:: CPN1;CYP11B;CYPXIB1;cytochrome P-450c11;cytochrome P450 11B1, mitochondrial;cytochrome p450 XIB1;cytochrome P450, family 11, subfamily B, polypeptide 1;cytochrome P450, subfamily XIB (steroid 11-beta-hydroxylase), polypeptide 1;cytochrome P450C11;FHI;P450C11;Steroid 11-beta-hydroxylase;steroid 11-beta-hydroxylase, CYP11B1;steroid 11-beta-monooxygenase
Weitere Details:: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and is involved in the conversion of progesterone to cortisol in the adrenal cortex. Mutations in this gene cause congenital adrenal hyperplasia due to 11-beta-hydroxylase deficiency. Transcript variants encoding different isoforms have been noted for this gene.