XPNPEP3 Polyclonal Antibody

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£195.30

War £217.00

SKU:: E-AB-66369
Zusätzliche Namen:: APP3,ICP55,NPHPL1,XPNPEP3
Anwendung:: IF
Konzentration:: 1 mg/ml
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Elabscience
Host:: Rabbit
Reaktivitäten:: Human, Mouse, Rat
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:: Recombinant fusion protein of human XPNPEP3 (NP_071381.1).
Uniprot:: Q9NQH7
Synonyme:: Aminopeptidase P3;APP3;ICP55;Intermediate Cleaving Peptidase 55;NPHPL1;probable Xaa-Pro aminopeptidase 3;X-Pro aminopeptidase 3;X-prolyl aminopeptidase 3, mitochondrial;xaa-Pro aminopeptidase 3
Weitere Details:: The protein encoded by this gene belongs to the family of X-pro-aminopeptidases that utilize a metal cofactor, and remove the N-terminal amino acid from peptides with a proline residue in the penultimate position. This protein has been shown to localize to the mitochondria of renal cells, and have a role in ciliary function. Mutations in this gene are associated with nephronophthisis-like nephropathy-1. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene, however, expression of some of these isoforms in vivo is not known.