BIRC3 Polyclonal Antibody

Größe

£195.30

War £217.00

SKU:: E-AB-65709
Zusätzliche Namen:: AIP1,API2,BIRC3,CIAP2,HAIP1,HIAP1,MALT2,MIHC,RNF49,c-IAP2
Anwendung:: IF
Konzentration:: 1 mg/ml
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Elabscience
Host:: Rabbit
Reaktivitäten:: Human, Mouse, Rat
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:: Recombinant fusion protein of human BIRC3 (NP_001156.1).
Uniprot:: Q13489
Synonyme:: AIP1;API2;apoptosis inhibitor 2;baculoviral IAP repeat-containing protein 3;c-IAP2;cellular inhibitor of apoptosis 2;CIAP2;HAIP1;HIAP1;IAP homolog C;IAP-1;inhibitor of apoptosis protein 1;MALT2;mammalian IAP homolog C;MIHC;RING finger protein 49;RING-type E3 ubiquitin transferase BIRC3;RNF49;TNFR2-TRAF signaling complex protein;TNFR2-TRAF-signaling complex protein 1
Weitere Details:: This gene encodes a member of the IAP family of proteins that inhibit apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. The encoded protein inhibits apoptosis induced by serum deprivation but does not affect apoptosis resulting from exposure to menadione, a potent inducer of free radicals. It contains 3 baculovirus IAP repeats and a ring finger domain. Transcript variants encoding the same isoform have been identified.