PUS1 Polyclonal Antibody

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£195.30

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SKU:: E-AB-65598
Zusätzliche Namen:: MLASA1,PUS1
Anwendung:: WB
Konzentration:: 1 mg/ml
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Elabscience
Host:: Rabbit
Reaktivitäten:: Human
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:: Recombinant fusion protein of human PUS1 (NP_079491.2).
Uniprot:: Q9Y606
Synonyme:: mitochondrial tRNA pseudouridine synthase A;MLASA1;pseudouridylate synthase 1;tRNA pseudouridine synthase A;tRNA pseudouridine synthase A, mitochondrial;tRNA pseudouridine(38-40) synthase;tRNA pseudouridylate synthase I;tRNA uridine isomerase I;tRNA-uridine isomerase I
Weitere Details:: This gene encodes a pseudouridine synthase that converts uridine to pseudouridine once it has been incorporated into an RNA molecule. The encoded enzyme may play an essential role in tRNA function and in stabilizing the secondary and tertiary structure of many RNAs. A mutation in this gene has been linked to mitochondrial myopathy and sideroblastic anemia. Alternate splicing results in multiple transcript variants.