DNM2 Polyclonal Antibody

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£195.30

War £217.00

SKU:: E-AB-65563
Zusätzliche Namen:: CMT2M,CMTDI1,CMTDIB,DI-CMTB,DNM2,DYN2,DYNII,LCCS5,dynamin-2
Anwendung:: WB
Konzentration:: 1 mg/ml
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Elabscience
Host:: Rabbit
Reaktivitäten:: Mouse, Rat
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:: Recombinant fusion protein of human DNM2 (NP_004936.2).
Uniprot:: P50570
Synonyme:: CMT2M;CMTDI1;CMTDIB;DI-CMTB;DYN2;dynamin II;dynamin-2;DYNII;LCCS5
Weitere Details:: Dynamins represent one of the subfamilies of GTP-binding proteins. These proteins share considerable sequence similarity over the N-terminal portion of the molecule, which contains the GTPase domain. Dynamins are associated with microtubules. They have been implicated in cell processes such as endocytosis and cell motility, and in alterations of the membrane that accompany certain activities such as bone resorption by osteoclasts. Dynamins bind many proteins that bind actin and other cytoskeletal proteins. Dynamins can also self-assemble, a process that stimulates GTPase activity. Five alternatively spliced transcripts encoding different proteins have been described. Additional alternatively spliced transcripts may exist, but their full-length nature has not been determined.