ZBED1 Polyclonal Antibody

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£195.30

War £217.00

SKU:: E-AB-65540
Zusätzliche Namen:: ALTE,DREF,TRAMP,ZBED1,hDREF
Anwendung:: IF
Konzentration:: 1 mg/ml
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Elabscience
Host:: Rabbit
Reaktivitäten:: Human
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:: Recombinant fusion protein of human ZBED1 (NP_001164607.1).
Uniprot:: O96006
Synonyme:: Ac-like transposable element;ALTE;BED-type zinc finger domain-containing protein 1;DNA replication-related element binding factor;DREF;dREF homolog;E3 SUMO-protein ligase ZBED1;hDREF;Putative Ac-like transposable element;TRAMP;zinc finger BED domain-containing protein 1
Weitere Details:: This gene is located in the pseudoautosomal region 1 (PAR1) of X and Y chromosomes. It was earlier identified as a gene with similarity to Ac transposable elements, however, was found not to have transposase activity. Later studies show that this gene product is localized in the nucleus and functions as a transcription factor. It binds to DNA elements found in the promoter regions of several genes related to cell proliferation, such as histone H1, hence may have a role in regulating genes related to cell proliferation. Alternatively spliced transcript variants with different 5' untranslated region have been found for this gene.