ADNP Polyclonal Antibody

Größe

£195.30

War £217.00

SKU:: E-AB-65484
Zusätzliche Namen:: ADNP,ADNP1,HVDAS,MRD28
Anwendung:: IF
Konzentration:: 1 mg/ml
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Elabscience
Host:: Rabbit
Reaktivitäten:: Human, Mouse
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:: Recombinant fusion protein of human ADNP (NP_056154.1).
Uniprot:: Q9H2P0
Synonyme:: activity-dependent neuroprotective protein;activity-dependent neuroprotector;activity-dependent neuroprotector homeobox protein;ADNP homeobox 1;ADNP1;HVDAS;MRD28
Weitere Details:: Vasoactive intestinal peptide is a neuroprotective factor that has a stimulatory effect on the growth of some tumor cells and an inhibitory effect on others. This gene encodes a protein that is upregulated by vasoactive intestinal peptide and may be involved in its stimulatory effect on certain tumor cells. The encoded protein contains one homeobox and nine zinc finger domains, suggesting that it functions as a transcription factor. This gene is also upregulated in normal proliferative tissues. Finally, the encoded protein may increase the viability of certain cell types through modulation of p53 activity. Alternatively spliced transcript variants encoding the same protein have been described.