UBQLN1 Polyclonal Antibody

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£195.30

War £217.00

SKU:: E-AB-65316
Zusätzliche Namen:: DA41,DSK2,PLIC-1,UBQLN1,UBQN,XDRP1
Anwendung:: WB
Konzentration:: 1 mg/ml
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Elabscience
Host:: Rabbit
Reaktivitäten:: Mouse, Rat
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:: Recombinant fusion protein of human UBQLN1 (NP_038466.2).
Uniprot:: Q9UMX0
Synonyme:: DA41;DSK2;hPLIC-1;PLIC-1;protein linking IAP with cytoskeleton 1;testicular tissue protein Li 219;ubiquilin-1;UBQN;XDRP1
Weitere Details:: This gene encodes an ubiquitin-like protein (ubiquilin) that shares a high degree of similarity with related products in yeast, rat and frog. Ubiquilins contain an N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. They physically associate with both proteasomes and ubiquitin ligases, and thus are thought to functionally link the ubiquitination machinery to the proteasome to affect in vivo protein degradation. This ubiquilin has also been shown to modulate accumulation of presenilin proteins, and it is found in lesions associated with Alzheimer's and Parkinson's disease. Two transcript variants encoding different isoforms have been found for this gene.