EEF1E1 Polyclonal Antibody

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£195.30

War £217.00

SKU:: E-AB-65282
Zusätzliche Namen:: AIMP3,EEF1E1,P18
Anwendung:: WB, IF
Konzentration:: 1 mg/ml
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Elabscience
Host:: Rabbit
Reaktivitäten:: Human, Mouse, Rat
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:: A synthetic peptide of human EEF1E1 (NP_004271.1).
Uniprot:: O43324
Synonyme:: AIMP3;aminoacyl tRNA synthetase complex-interacting multifunctional protein 3;ARS-interacting multifunctional protein 3;Elongation factor p18;eukaryotic translation elongation factor 1 epsilon-1;multisynthase complex auxiliary component p18;P18;p18 component of aminoacyl-tRNA synthetase complex
Weitere Details:: This gene encodes a multifunctional protein that localizes to both the cytoplasm and nucleus. In the cytoplasm, the encoded protein is an auxiliary component of the macromolecular aminoacyl-tRNA synthase complex. However, its mouse homolog has been shown to translocate to the nucleus in response to DNA damage, and it plays a positive role in ATM/ATR-mediated p53 activation. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream MUTED (muted homolog) gene. An EEF1E1-related pseudogene has been identified on chromosome 2.