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E-AB-65278

TRIP4 Polyclonal Antibody

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£195.30

War £217.00

SKU:
E-AB-65278
Zusätzliche Namen:
ASC-1,ASC1,HsT17391,MDCDC,SMABF1,TRIP4,ZC2HC5
Anwendung:
IHC
Konzentration:
1 mg/ml
Aufreinigung:
Affinity Purified
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Host:
Rabbit
Reaktivitäten:
Human, Mouse, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Recombinant fusion protein of human TRIP4 (NP_057297.2).
Uniprot:
Q15650
Synonyme:
activating signal cointegrator 1;ASC-1;ASC1;HsT17391;MDCDC;SMABF1;thyroid receptor-interacting protein 4;TR-interacting protein 4;TRIP-4;ZC2HC5;zinc finger, C2HC5-type
Weitere Details:
This gene encodes a subunit of the tetrameric nuclear activating signal cointegrator 1 (ASC-1) complex, which associates with transcriptional coactivators, nuclear receptors and basal transcription factors to facilitate nuclear receptors-mediated transcription. This protein is localized in the nucleus and contains an E1A-type zinc finger domain, which mediates interaction with transcriptional coactivators and ligand-bound nuclear receptors, such as thyroid hormone receptor and retinoid X receptor alpha, but not glucocorticoid receptor. Mutations in this gene are associated with spinal muscular atrophy with congenital bone fractures-1 (SMABF1).
Versandbedingungen:
Blue Ice