CNBP Polyclonal Antibody

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£195.30

War £217.00

SKU:: E-AB-65202
Zusätzliche Namen:: CNBP,CNBP1,DM2,PROMM,RNF163,ZCCHC22,ZNF9
Anwendung:: IF
Konzentration:: 1 mg/ml
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Elabscience
Host:: Rabbit
Reaktivitäten:: Human, Mouse
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:: A synthetic peptide of human CNBP (NP_001120668.1).
Uniprot:: P62633
Synonyme:: cellular nucleic acid-binding protein;CNBP1;DM2;erythroid differentiation-related;PROMM;RNF163;sterol regulatory element-binding protein;ZCCHC22;zinc finger protein 273;Zinc finger protein 9;zinc finger protein 9 (a cellular retroviral nucleic acid binding protein);ZNF9
Weitere Details:: This gene encodes a nucleic-acid binding protein with seven zinc-finger domains. The protein has a preference for binding single stranded DNA and RNA. The protein functions in cap-independent translation of ornithine decarboxylase mRNA, and may also function in sterol-mediated transcriptional regulation. A CCTG expansion from <30 repeats to 75-11000 repeats in the first intron of this gene results in myotonic dystrophy type 2. Multiple transcript variants encoding different isoforms have been found for this gene.