Polyclonal AntibodyPC1 Polyclonal Antibody

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£195.30

War £217.00

SKU:: E-AB-65139
Zusätzliche Namen:: PAB1,PABP,PABP1,PABPC1,PABPC2,PABPL1
Anwendung:: IHC, IF
Konzentration:: 1 mg/ml
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Elabscience
Host:: Rabbit
Reaktivitäten:: Human, Mouse, Rat
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:: A synthetic peptide of human PABPC1 (NP_002559.2).
Uniprot:: P11940
Synonyme:: PAB1;PABP;PABP1;PABPC2;PABPL1;poly(A) binding protein, cytoplasmic 2;polyadenylate-binding protein 1
Weitere Details:: This gene encodes a poly(A) binding protein. The protein shuttles between the nucleus and cytoplasm and binds to the 3' poly(A) tail of eukaryotic messenger RNAs via RNA-recognition motifs. The binding of this protein to poly(A) promotes ribosome recruitment and translation initiation, it is also required for poly(A) shortening which is the first step in mRNA decay. The gene is part of a small gene family including three protein-coding genes and several pseudogenes.